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Test Name:Alpha 1 antitrypsin
Test Number:18
Collect:1.0 mL Serum - SST
Peds Collect:0.5 mL Serum - SST
Alternate Collect:1.0 mL EDTA plasma - Lavender
1.0 mL Heparin plasma - PST
Container:Serum Separator Tube (SST) or
AHL False Bottom Plasma/Serum Transport Tube
Processing:SST or PST - Spin
Lavender (EDTA) - Spin and separate
Transport/Stability:Refrigerated - 7 days
Alternate Names:A1A
82103.0
Performing Lab:AHL - Immunology; I
Days Set Up:Tu, Fr
Expected TAT:1 - 3 days
Ref. Ranges:90 - 200 mg/dL
Collection/
Processing Details:
If unable to send to Central Lab within 48 hours, aliquot and freeze.

Alpha 1 Antitrypsin Information: α1-Antitrypsin is an important, positive acute phase reactant found in elevated concentrations in inflammatory processes (e.g. infectious and rheumatoid diseases), tissue necrosis, malignancy and traumas. Inflammation of the liver parenchymal cells is often accompanied by elevated α1-antitrypsin levels, althoughlevels of other acute phase reactants are not affected. Acute hereditary α1-antitrypsin deficiency is suspected in cases of neonatal hepatitis accompanied by progressive liver cirrhosis in early childhood. It is also suspected when severe pulmonary emphysema occurs in adults due to the prevalence of leukocyte elastase, which can lead to unrestrained proteolytic degradation of the pulmonary parenchymal cells.
Method:Nephelometry
CPT Codes:82103
Date Created:07/11/2007
Revised Date:06/19/2017