1.0 mL EDTA plasma - Lavender
1.0 mL Heparin plasma - PST
Serum Separator Tube (SST) or
AHL False Bottom Plasma/Serum Transport Tube
SST or PST - Spin
Lavender (EDTA) - Spin and separate
Refrigerated - 7 days
AHL - Immunology; I
Days Set Up:
1 - 3 days
90 - 200 mg/dL
Collection/ Processing Details:
If unable to send to Central Lab within 48 hours, aliquot and freeze.
Alpha 1 Antitrypsin Information: α1-Antitrypsin is an important, positive acute phase reactant found in elevated concentrations in
inflammatory processes (e.g. infectious and rheumatoid diseases), tissue necrosis, malignancy and traumas.
Inflammation of the liver parenchymal cells is often accompanied by elevated α1-antitrypsin levels, althoughlevels of other acute phase reactants are not affected.
Acute hereditary α1-antitrypsin deficiency is suspected in cases of neonatal hepatitis
accompanied by progressive liver cirrhosis in early childhood. It is also suspected when severe pulmonary emphysema occurs in adults due to the prevalence of leukocyte elastase,
which can lead to unrestrained proteolytic degradation of the pulmonary