Submit processed tissue block or tissue section mounted on a charged, unstained slide
AHL - Immunohistochemistry
Days Set Up:
Mo - Fr
1 - 2 days
If requested, an interpretive report will be provided All IHC stains will include a positive control tissue
Collection/ Processing Details:
PSA is a glycoprotein found in normal and neoplastic secretory and ductal prostatic epithelium
Cytoplasmic based staining.
PSA is expressed by >99% of prostatic carcinomas (although poorly differentiated prostatic carcinomas may express this antigen weakly and/or focally)
PSA is a very durable antigen, even with prolonged formalin fixation
In vast majority of cases, prostatic acid phosphatase is not needed with PSA. However, we use prostatic acid phosphatase in weakly suspiciously PSA positive or PSA negative tumors in which prostatic origin is strongly suspected.