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Test Name:Porphobilinogen, quantitative, random urine
Test Number:994
Collect:3.0 mL urine (random)
Container:LabCorp Amber 4mL screw-cap polypropylene frozen transport tube labelled as urine
Processing:Freeze and protect from light
Transport/Stability:
Alternate Names:MSO
G299 LAB994
Performing Lab:LabCorp Burlington (003053); R-NX
Days Set Up:Mo, We, Fr
Expected TAT:2 - 4 days
Ref. Ranges:0.0 − 2.0 mg/L
Collection/
Processing Details:
Useful for:
Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attack types of porphyrias associated with neurologic and/or psychiatric symptoms. Detect porphyrias and porphyrinurias. Acute intermittent porphyria is characterized by excretion of porphobilinogen and δ-aminolevulinic acid in urine during acute attacks but not during latency. Increased porphobilinogen may be caused also by variegate porphyria or hereditary coproporphyria. Increased urine values are seen in the intoxication porphyrias (heavy metals, halogenated solvents, certain drugs).


On collection of random urine, it is advisable NOT to use first voided morning specimen, late evening specimen after 8 PM, or specimen obtained following excessive fluid intake. Transfer the urine into a LabCorp AMBER plastic frozen transport tube with amber cap (LabCorp ID 78656). If ordered with delta ALA, pH must be <6. Label the container with the patient's name and date. The specimen should be FROZEN immediately and maintained frozen until tested. (If amber tube and cap are not available, cover a clear plastic transport tube COMPLETELY from top to bottom with aluminum foil.
Method:Chromatography/spectrophotometry
CPT Codes:84110
Supply Connection:LabCorp Amber 4mL screw-cap polypropylene frozen transport tube
Date Created:05/24/2019
Revised Date:05/24/2019