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Test Name:Prostaglandin D2, serum/plasma
Test Number:994
Collect:3.0 mL serum - SST
Minimum Volume:1.0 mL
Alternate Collect:3.0 mL EDTA plasma - lavender
Container:LabCorp screw-capped purple frozen plastic transport tube labelled as serum or EDTA plasma
Processing:Spin, separate and freeze.
Transport/Stability:Frozen - 60 days
Alternate Names:PG D2
Prostaglandins: D2,

MSO
LAB994
Performing Lab:Interscience Institute ( ) via LabCorp (801225); R-NX
Days Set Up:
Expected TAT:10 - 17 days
Ref. Ranges:35 - 115 pg/ml
Collection/
Processing Details:
Useful for:
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin.


Patient preparation
Aspirin, indomethacin, or anti-inflammatory medications should be discontinued, if possible, at least 48 hours prior to collection. 
Method:EIA/ELISA
CPT Codes:84150
Date Created:05/24/2019
Revised Date:06/03/2019