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Test Name:Aldosterone, 24 hr urine
Test Number:23
Collect:24 hr urine collection
Container:24 Hr Urine Conatiner + 25 mL 50 % Acetic Acid
Submit 10 mL aliquot in 60 mL Mayo Urine Aliquot Bottle
Processing:Submit entire specimen or a 10 mL aliquot in a Mayo Urine Aliquot Bottle. 24-hr volume is required.
Transport/Stability:Refrigerated (preferred) - 28 days
Frozen (OK) - 28 days
Ambient (OK with preservative) - 14 days
Alternate Names:A24
82088.2
Performing Lab:Mayo Clinic Laboratories (ALDU); R-MM
Days Set Up:Tu, Th; 1 p.m.
Expected TAT:2 - 8 days
Ref. Ranges:≥1 year: 2.0-20.0 µg/24 hr
Collection/
Processing Details:
Useful for the investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome)

Patient preparation
Spironolactone (Aldactone) should be discontinued for 4 to 6 weeks before testing.

Add 25 mL 50% acetic acid at start of collection. Use 15 mL of 50% acetic acid for pediatric patients < 5 years old. Preservative is intended to achieve a pH of 2.0 - 4.0.
Record total volume of urineand preservative used on aliquot bottle.
Alternate acceptable preservatives
Aldosterone with Sodium is Mayo test ALDNA.

Method:Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
CPT Codes:82088
MSDS:Acetic Acid
Related Article:Clinic Preservative Instructions
Hospital Specific Information:
Additional Information: Mayo Urine Preservatives - Collection and Transportation for 24-Hr Urine Specimens
Date Created:09/18/2007
Revised Date:11/14/2018